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Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs

HIV’s ability to establish latent reservoirs of reactivation-competent virus is the major barrier to cure. “Shock and kill” methods consisting of latency-reversing agents (LRAs) followed by elimination of reactivating cells through cytopathic effects are under active development. However, the clinic...

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Detalles Bibliográficos
Autores principales: Brockman, Mark A., Jones, R. Brad, Brumme, Zabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591506/
https://www.ncbi.nlm.nih.gov/pubmed/26483795
http://dx.doi.org/10.3389/fimmu.2015.00506