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Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs
HIV’s ability to establish latent reservoirs of reactivation-competent virus is the major barrier to cure. “Shock and kill” methods consisting of latency-reversing agents (LRAs) followed by elimination of reactivating cells through cytopathic effects are under active development. However, the clinic...
Autores principales: | Brockman, Mark A., Jones, R. Brad, Brumme, Zabrina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591506/ https://www.ncbi.nlm.nih.gov/pubmed/26483795 http://dx.doi.org/10.3389/fimmu.2015.00506 |
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