Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion

Up-regulation of the cytoskeleton linker protein ezrin frequently occurs in aggressive cancer types and is closely linked with metastatic progression. However, the underlying molecular mechanisms detailing how ezrin is involved in the invasive and metastatic phenotype remain unclear. Here we report...

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Detalles Bibliográficos
Autores principales: Hoskin, Victoria, Szeto, Alvin, Ghaffari, Abdi, Greer, Peter A., Côté, Graham P., Elliott, Bruce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591691/
https://www.ncbi.nlm.nih.gov/pubmed/26246600
http://dx.doi.org/10.1091/mbc.E14-12-1584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591691/
https://www.ncbi.nlm.nih.gov/pubmed/26246600
http://dx.doi.org/10.1091/mbc.E14-12-1584

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