Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition

Two large phosphatidylinositol 3-kinase–related protein kinases (PIKKs), ATM and ATR, play a central role in the DNA damage response pathway. PIKKs contain a highly conserved extreme C-terminus called the FRAP-ATM-TRRAP-C-terminal (FATC) domain. In budding yeast, ATM and ATR correspond to Tel1 and M...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogi, Hiroo, Goto, Greicy H., Ghosh, Avik, Zencir, Sevil, Henry, Everett, Sugimoto, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591692/
https://www.ncbi.nlm.nih.gov/pubmed/26246601
http://dx.doi.org/10.1091/mbc.E15-05-0259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591692/
https://www.ncbi.nlm.nih.gov/pubmed/26246601
http://dx.doi.org/10.1091/mbc.E15-05-0259

Ejemplares similares