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Angiotensin II Type 1 Receptor-Mediated Electrical Remodeling in Mouse Cardiac Myocytes

We recently characterized an autocrine renin angiotensin system (RAS) in canine heart. Activation of Angiotensin II Type 1 Receptors (AT(1)Rs) induced electrical remodeling, including inhibition of the transient outward potassium current I(to), prolongation of the action potential (AP), increased ca...

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Detalles Bibliográficos
Autores principales: Kim, Jeremy, Gao, Junyuan, Cohen, Ira S., Mathias, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591968/
https://www.ncbi.nlm.nih.gov/pubmed/26430746
http://dx.doi.org/10.1371/journal.pone.0138711