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Enhanced Immune Response to DNA Vaccine Encoding Bacillus anthracis PA-D4 Protects Mice against Anthrax Spore Challenge

Anthrax has long been considered the most probable bioweapon-induced disease. The protective antigen (PA) of Bacillus anthracis plays a crucial role in the pathogenesis of anthrax. In the current study, we evaluated the efficiency of a genetic vaccination with the fourth domain (D4) of PA, which is...

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Detalles Bibliográficos
Autores principales: Kim, Na Young, Chang, Dong Suk, Kim, Yeonsu, Kim, Chang Hwan, Hur, Gyeung Haeng, Yang, Jai Myung, Shin, Sungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591996/
https://www.ncbi.nlm.nih.gov/pubmed/26430894
http://dx.doi.org/10.1371/journal.pone.0139671