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Enhanced Immune Response to DNA Vaccine Encoding Bacillus anthracis PA-D4 Protects Mice against Anthrax Spore Challenge
Anthrax has long been considered the most probable bioweapon-induced disease. The protective antigen (PA) of Bacillus anthracis plays a crucial role in the pathogenesis of anthrax. In the current study, we evaluated the efficiency of a genetic vaccination with the fourth domain (D4) of PA, which is...
Autores principales: | Kim, Na Young, Chang, Dong Suk, Kim, Yeonsu, Kim, Chang Hwan, Hur, Gyeung Haeng, Yang, Jai Myung, Shin, Sungho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591996/ https://www.ncbi.nlm.nih.gov/pubmed/26430894 http://dx.doi.org/10.1371/journal.pone.0139671 |
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