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Half-Barrels Derived from a (β/α)(8) Barrel β-Glycosidase Undergo an Activation Process

The evolution of (β/α)(8) barrel proteins is currently thought to have involved the fusion of two (β/α)(4) half-barrels, thereby conferring stability on the protein structure. After the formation of a whole (β/α)(8) barrel, this structure could evolve and diverge to form fully active enzymes. Intere...

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Detalles Bibliográficos
Autores principales: Beton, Daniela, Marana, Sandro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591997/
https://www.ncbi.nlm.nih.gov/pubmed/26431042
http://dx.doi.org/10.1371/journal.pone.0139673