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Using Mathematical Modelling to Explore Hypotheses about the Role of Bovine Epithelium Structure in Foot-And-Mouth Disease Virus-Induced Cell Lysis

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. FMD virus (FMDV) shows a strong tropism for epithelial cells, and FMD is characterised by cell lysis and the development of vesicular lesions in certain epithelial tissues (for example, the tongue). By contrast, ot...

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Detalles Bibliográficos
Autores principales: Giorgakoudi, Kyriaki, Gubbins, Simon, Ward, John, Juleff, Nicholas, Zhang, Zhidong, Schley, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592007/
https://www.ncbi.nlm.nih.gov/pubmed/26431527
http://dx.doi.org/10.1371/journal.pone.0138571