Comparative Analysis of Cell-Associated HIV DNA Levels in Cerebrospinal Fluid and Peripheral Blood by Droplet Digital PCR

BACKGROUND: Measurement of HIV DNA-bearing cells in cerebrospinal fluid (CSF) is challenging because few cells are present. We present a novel application of the sensitive droplet digital (dd)PCR in this context. METHODS: We analyzed CSF cell pellets and paired peripheral blood mononuclear cells (PB...

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Detalles Bibliográficos
Autores principales: de Oliveira, Michelli Faria, Gianella, Sara, Letendre, Scott, Scheffler, Konrad, Kosakovsky Pond, Sergei L., Smith, Davey M., Strain, Matt, Ellis, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592012/
https://www.ncbi.nlm.nih.gov/pubmed/26431315
http://dx.doi.org/10.1371/journal.pone.0139510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592012/
https://www.ncbi.nlm.nih.gov/pubmed/26431315
http://dx.doi.org/10.1371/journal.pone.0139510

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