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Biofilm Formation Mechanisms of Pseudomonas aeruginosa Predicted via Genome-Scale Kinetic Models of Bacterial Metabolism

A hallmark of Pseudomonas aeruginosa is its ability to establish biofilm-based infections that are difficult to eradicate. Biofilms are less susceptible to host inflammatory and immune responses and have higher antibiotic tolerance than free-living planktonic cells. Developing treatments against bio...

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Detalles Bibliográficos
Autores principales: Vital-Lopez, Francisco G., Reifman, Jaques, Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592021/
https://www.ncbi.nlm.nih.gov/pubmed/26431398
http://dx.doi.org/10.1371/journal.pcbi.1004452