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The engineered Salmonella typhimurium inhibits tumorigenesis in advanced glioma
OBJECTIVE: To explore the antitumor role of the attenuated Salmonella typhimurium ΔppGpp with inducible cytolysin A (ClyA) in advanced stage of glioma. MATERIALS AND METHODS: The C6 rat glioma cells were orthotopically implanted by surgery into the caudate nucleus of rat brains. The rats were then r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592054/ https://www.ncbi.nlm.nih.gov/pubmed/26451114 http://dx.doi.org/10.2147/OTT.S86899 |