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Subcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail Anchor

The canonical protein tyrosine phosphatase PTP1B is an important regulator of diverse cellular signaling networks. PTP1B has long been thought to exert its influence solely from its perch on the endoplasmic reticulum (ER); however, an additional subpopulation of PTP1B has recently been detected in m...

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Detalles Bibliográficos
Autores principales: Fueller, Julia, Egorov, Mikhail V., Walther, Kirstin A., Sabet, Ola, Mallah, Jana, Grabenbauer, Markus, Kinkhabwala, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592070/
https://www.ncbi.nlm.nih.gov/pubmed/26431424
http://dx.doi.org/10.1371/journal.pone.0139429