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The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma

Synthetic lethality arises when a combination of mutations in two or more genes leads to cell death. However, the prognostic role of concordant overexpression of synthetic lethality genes in protein level rather than a combination of mutations is not clear. In this study, we explore the prognostic r...

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Detalles Bibliográficos
Autores principales: Hwang, Jau-Chung, Sung, Wen-Wei, Tu, Hung-Pin, Hsieh, Kun-Chou, Yeh, Chung-Min, Chen, Chih-Jung, Tai, Hui-Chun, Hsu, Chao-Tien, Shieh, Grace S., Chang, Jan-Gowth, Yeh, Kun-Tu, Liu, Ta-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592204/
https://www.ncbi.nlm.nih.gov/pubmed/26431531
http://dx.doi.org/10.1371/journal.pone.0139435