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Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells

Epstein-Barr virus (EBV) is a human herpesvirus associated with B-cell and epithelial cell malignancies. EBV lytically infects normal differentiated oral epithelial cells, where it causes a tongue lesion known as oral hairy leukoplakia (OHL) in immunosuppressed patients. However, the cellular mechan...

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Detalles Bibliográficos
Autores principales: Nawandar, Dhananjay M., Wang, Anqi, Makielski, Kathleen, Lee, Denis, Ma, Shidong, Barlow, Elizabeth, Reusch, Jessica, Jiang, Ru, Wille, Coral K., Greenspan, Deborah, Greenspan, John S., Mertz, Janet E., Hutt-Fletcher, Lindsey, Johannsen, Eric C., Lambert, Paul F., Kenney, Shannon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592227/
https://www.ncbi.nlm.nih.gov/pubmed/26431332
http://dx.doi.org/10.1371/journal.ppat.1005195