A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties

BACKGROUND: Half-life extension strategies have gained increasing interest to improve the pharmacokinetic and pharmacodynamic properties of protein therapeutics. Recently, we established an immunoglobulin-binding domain (IgBD) from streptococcal protein G (SpG(C3)) as module for half-life extension....

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Detalles Bibliográficos
Autores principales: Unverdorben, Felix, Hutt, Meike, Seifert, Oliver, Kontermann, Roland E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592230/
https://www.ncbi.nlm.nih.gov/pubmed/26430884
http://dx.doi.org/10.1371/journal.pone.0139838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592230/
https://www.ncbi.nlm.nih.gov/pubmed/26430884
http://dx.doi.org/10.1371/journal.pone.0139838

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