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The Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofilm Growth In Vitro

Streptococcus pneumoniae persist in the human nasopharynx within organized biofilms. However, expansion to other tissues may cause severe infections such as pneumonia, otitis media, bacteremia, and meningitis, especially in children and the elderly. Bacteria within biofilms possess increased toleran...

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Detalles Bibliográficos
Autores principales: Yadav, Mukesh Kumar, Go, Yoon Young, Chae, Sung-Won, Song, Jae-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592238/
https://www.ncbi.nlm.nih.gov/pubmed/26431532
http://dx.doi.org/10.1371/journal.pone.0139238