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FTO Is Associated with Aortic Valve Stenosis in a Gender Specific Manner of Heterozygote Advantage: A Population-Based Case-Control Study

BACKGROUND: Single nucleotide polymorphisms (SNPs) within the Fat mass and obesity associated (FTO) gene have been linked with increased body weight. However, the data on an association of FTO with cardiovascular diseases remains conflicting. Therefore, we ascertained whether FTO is associated with...

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Detalles Bibliográficos
Autores principales: Thron, Cindy, Akhyari, Payam, Godehardt, Erhard, Lichtenberg, Artur, Rüther, Ulrich, Seehaus, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592246/
https://www.ncbi.nlm.nih.gov/pubmed/26431034
http://dx.doi.org/10.1371/journal.pone.0139419