Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

The ability of phagocytes to clear pathogens is an essential attribute of the innate immune response. The role of signaling lipid molecules such as phosphoinositides is well established, but the role of membrane sphingolipids in phagocytosis is largely unknown. Using a genetic approach and small mol...

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Detalles Bibliográficos
Autores principales: Tafesse, Fikadu G., Rashidfarrokhi, Ali, Schmidt, Florian I., Freinkman, Elizaveta, Dougan, Stephanie, Dougan, Michael, Esteban, Alexandre, Maruyama, Takeshi, Strijbis, Karin, Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592247/
https://www.ncbi.nlm.nih.gov/pubmed/26431038
http://dx.doi.org/10.1371/journal.ppat.1005188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592247/
https://www.ncbi.nlm.nih.gov/pubmed/26431038
http://dx.doi.org/10.1371/journal.ppat.1005188

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