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Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

Excessive synovial osteoclastogenesis is a hallmark of rheumatoid arthritis (RA). Concomitantly, local synovial changes comprise neuronal components of the peripheral sympathetic nervous system. Here, we wanted to analyze if collagen-induced arthritis (CIA) alters bone marrow-derived macrophage (BMM...

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Detalles Bibliográficos
Autores principales: Muschter, Dominique, Schäfer, Nicole, Stangl, Hubert, Straub, Rainer H., Grässel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592252/
https://www.ncbi.nlm.nih.gov/pubmed/26431344
http://dx.doi.org/10.1371/journal.pone.0139726