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Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma

BACKGROUND: North central China has some of the highest rates of esophageal squamous cell carcinoma in the world with cumulative mortality surpassing 20%. Mitochondrial DNA (mtDNA) accumulates more mutations than nuclear DNA and because of its high abundance has been proposed as a early detection de...

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Detalles Bibliográficos
Autores principales: Abnet, Christian C, Huppi, Konrad, Carrera, Ana, Armistead, David, McKenney, Keith, Hu, Nan, Tang, Ze-Zong, Taylor, Philip R, Dawsey, Sanford M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC459226/
https://www.ncbi.nlm.nih.gov/pubmed/15230979
http://dx.doi.org/10.1186/1471-2407-4-30