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CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma

Recent studies have described a number of genes that are frequently altered in medulloblastoma tumors and that have putative key roles in the development of the disease. We hypothesized that common germline genetic variations in these genes may be associated with medulloblastoma development. Based o...

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Detalles Bibliográficos
Autores principales: Dahlin, Anna M., Hollegaard, Mads V., Wibom, Carl, Andersson, Ulrika, Hougaard, David M., Deltour, Isabelle, Hjalmars, Ulf, Melin, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592490/
https://www.ncbi.nlm.nih.gov/pubmed/26290144
http://dx.doi.org/10.1007/s11060-015-1891-1