Cargando…

Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family

Tandem C2H2-type zinc finger proteins (ZFPs) constitute the largest transcription factor family in animals. Tandem-ZFPs bind DNA in a sequence-specific manner through arrays of multiple zinc finger domains that allow high flexibility and specificity in target recognition. In tetrapods, a large propo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wolf, Gernot, Greenberg, David, Macfarlan, Todd S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592553/
https://www.ncbi.nlm.nih.gov/pubmed/26435754
http://dx.doi.org/10.1186/s13100-015-0050-8