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Application of Molecular Modeling to Development of New Factor Xa Inhibitors

In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein is an attractive target for development of new blood coagulation inhibitors. Factor Xa is more effective and convenient target for creation of...

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Detalles Bibliográficos
Autores principales: Sulimov, Vladimir B., Gribkova, Irina V., Kochugaeva, Maria P., Katkova, Ekaterina V., Sulimov, Alexey V., Kutov, Danil C., Shikhaliev, Khidmet S., Medvedeva, Svetlana M., Krysin, Michael Yu., Sinauridze, Elena I., Ataullakhanov, Fazoil I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592935/
https://www.ncbi.nlm.nih.gov/pubmed/26484350
http://dx.doi.org/10.1155/2015/120802