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The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS

BACKGROUND: In recent years, genome wide association studies have identified many genetic variants that are consistently associated with common complex diseases, but the amount of heritability explained by these risk alleles is still low. Part of the missing heritability may be due to genetic hetero...

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Detalles Bibliográficos
Autores principales: Waltoft, Berit Lindum, Pedersen, Carsten Bøcker, Nyegaard, Mette, Hobolth, Asger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593225/
https://www.ncbi.nlm.nih.gov/pubmed/26319230
http://dx.doi.org/10.1186/s12881-015-0210-1