Improved OTU-picking using long-read 16S rRNA gene amplicon sequencing and generic hierarchical clustering

BACKGROUND: High-throughput bacterial 16S rRNA gene sequencing followed by clustering of short sequences into operational taxonomic units (OTUs) is widely used for microbiome profiling. However, clustering of short 16S rRNA gene reads into biologically meaningful OTUs is challenging, in part because...

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Detalles Bibliográficos
Autores principales: Franzén, Oscar, Hu, Jianzhong, Bao, Xiuliang, Itzkowitz, Steven H., Peter, Inga, Bashir, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593230/
https://www.ncbi.nlm.nih.gov/pubmed/26434730
http://dx.doi.org/10.1186/s40168-015-0105-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593230/
https://www.ncbi.nlm.nih.gov/pubmed/26434730
http://dx.doi.org/10.1186/s40168-015-0105-6

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