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A web portal for in-silico action potential predictions

INTRODUCTION: Multiple cardiac ion channels are prone to block by pharmaceutical compounds, and this can have large implications for cardiac safety. The effect of a compound on individual ion currents can now be measured in automated patch clamp screening assays. In-silico action potential models ar...

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Detalles Bibliográficos
Autores principales: Williams, Geoff, Mirams, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593298/
https://www.ncbi.nlm.nih.gov/pubmed/25963830
http://dx.doi.org/10.1016/j.vascn.2015.05.002