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A web portal for in-silico action potential predictions
INTRODUCTION: Multiple cardiac ion channels are prone to block by pharmaceutical compounds, and this can have large implications for cardiac safety. The effect of a compound on individual ion currents can now be measured in automated patch clamp screening assays. In-silico action potential models ar...
Autores principales: | Williams, Geoff, Mirams, Gary R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593298/ https://www.ncbi.nlm.nih.gov/pubmed/25963830 http://dx.doi.org/10.1016/j.vascn.2015.05.002 |
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