Selective killing of K-ras–transformed pancreatic cancer cells by targeting NAD(P)H oxidase

INTRODUCTION: Oncogenic activation of the K-ras gene occurs in >90% of pancreatic ductal carcinoma and plays a critical role in the pathogenesis of this malignancy. Increase of reactive oxygen species (ROS) has also been observed in a wide spectrum of cancers. This study aimed to investigate the...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Sun, Yi-Chen, Lu, Wen-Hua, Huang, Peng, Hu, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593348/
https://www.ncbi.nlm.nih.gov/pubmed/25963558
http://dx.doi.org/10.1186/s40880-015-0012-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593348/
https://www.ncbi.nlm.nih.gov/pubmed/25963558
http://dx.doi.org/10.1186/s40880-015-0012-z

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