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Structural analysis of tumor-related single amino acid mutations in human MxA protein
BACKGROUND: Human myxovirus resistant protein A (MxA), encoded by the myxovirus resistance 1 (Mx1) gene, is an interferon (IFN)-triggered dynamin-like multi-domain GTPase involved in innate immune responses against viral infections. Recent studies suggest that MxA is associated with several human ca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593380/ https://www.ncbi.nlm.nih.gov/pubmed/26411585 http://dx.doi.org/10.1186/s40880-015-0055-1 |