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A multilevel pan-cancer map links gene mutations to cancer hallmarks

BACKGROUND: A central challenge in cancer research is to create models that bridge the gap between the molecular level on which interventions can be designed and the cellular and tissue levels on which the disease phenotypes are manifested. This study was undertaken to construct such a model from fu...

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Detalles Bibliográficos
Autores principales: Knijnenburg, Theo A., Bismeijer, Tycho, Wessels, Lodewyk F. A., Shmulevich, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593384/
https://www.ncbi.nlm.nih.gov/pubmed/26369414
http://dx.doi.org/10.1186/s40880-015-0050-6