Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish

Antisense oligonucleotides (ASOs) are synthetic, single-strand RNA-DNA hybrids that induce catalytic degradation of complementary cellular RNAs via RNase H. ASOs are widely used as gene knockdown reagents in tissue culture and in Xenopus and mouse model systems. To test their effectiveness in zebraf...

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Detalles Bibliográficos
Autores principales: Pauli, Andrea, Montague, Tessa G., Lennox, Kim A., Behlke, Mark A., Schier, Alexander F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593562/
https://www.ncbi.nlm.nih.gov/pubmed/26436892
http://dx.doi.org/10.1371/journal.pone.0139504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593562/
https://www.ncbi.nlm.nih.gov/pubmed/26436892
http://dx.doi.org/10.1371/journal.pone.0139504

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