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Fractalkine signaling in regulation of insulin secretion: Mechanisms and potential therapeutic implications?

Fractalkine is a chemokine, which has been shown to play important roles in metabolic disease in both animal models and humans. Fractalkine is a key player in the accumulation of atherosclerotic plaques, and fractalkine receptor (CX3CR1) mutations have been implicated in obesity. Serum fractalkine l...

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Detalles Bibliográficos
Autores principales: Gregg, Brigid, Lumeng, Carey N, Bernal-Mizrachi, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593565/
https://www.ncbi.nlm.nih.gov/pubmed/25483879
http://dx.doi.org/10.4161/isl.27861