Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway

The endothelial receptor tyrosine kinase (RTK) Tie1 was discovered over 20 years ago, yet its precise function and mode of action remain enigmatic. To shed light on Tie1’s role in endothelial cell biology, we investigated a potential threonine phosphorylation site within the juxtamembrane domain of...

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Detalles Bibliográficos
Autores principales: Reinardy, Jessica L., Corey, Daniel M., Golzio, Christelle, Mueller, Sarah B., Katsanis, Nicholas, Kontos, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593579/
https://www.ncbi.nlm.nih.gov/pubmed/26436659
http://dx.doi.org/10.1371/journal.pone.0139614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593579/
https://www.ncbi.nlm.nih.gov/pubmed/26436659
http://dx.doi.org/10.1371/journal.pone.0139614

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