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A Retrospective Study on Genetic Heterogeneity within Treponema Strains: Subpopulations Are Genetically Distinct in a Limited Number of Positions

BACKGROUND: Pathogenic uncultivable treponemes comprise human and animal pathogens including agents of syphilis, yaws, bejel, pinta, and venereal spirochetosis in rabbits and hares. A set of 10 treponemal genome sequences including those of 4 Treponema pallidum ssp. pallidum (TPA) strains (Nichols,...

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Detalles Bibliográficos
Autores principales: Čejková, Darina, Strouhal, Michal, Norris, Steven J., Weinstock, George M., Šmajs, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593590/
https://www.ncbi.nlm.nih.gov/pubmed/26436423
http://dx.doi.org/10.1371/journal.pntd.0004110