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Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells

Arthritogenic alphaviruses, including Ross River virus (RRV) and chikungunya virus (CHIKV), are responsible for explosive epidemics involving millions of cases. These mosquito-transmitted viruses cause inflammation and injury in skeletal muscle and joint tissues that results in debilitating pain. We...

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Detalles Bibliográficos
Autores principales: Burrack, Kristina S., Tan, Jeslin J. L., McCarthy, Mary K., Her, Zhisheng, Berger, Jennifer N., Ng, Lisa F. P., Morrison, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593600/
https://www.ncbi.nlm.nih.gov/pubmed/26436766
http://dx.doi.org/10.1371/journal.ppat.1005191