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Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway

BACKGROUND: Current chemotherapeutic agents based on apoptosis induction are lacking in desired efficacy. Therefore, there is continuous effort to bring about new dimension in control and gradual eradication of cancer by means of ever evolving therapeutic strategies. Various forms of PCD are being i...

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Detalles Bibliográficos
Autores principales: Kumar, Deepak, Das, Bimolendu, Sen, Rupashree, Kundu, Priyanka, Manna, Alak, Sarkar, Avijit, Chowdhury, Chinmay, Chatterjee, Mitali, Das, Padma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593644/
https://www.ncbi.nlm.nih.gov/pubmed/26436418
http://dx.doi.org/10.1371/journal.pone.0139657