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Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway
BACKGROUND: Current chemotherapeutic agents based on apoptosis induction are lacking in desired efficacy. Therefore, there is continuous effort to bring about new dimension in control and gradual eradication of cancer by means of ever evolving therapeutic strategies. Various forms of PCD are being i...
Autores principales: | Kumar, Deepak, Das, Bimolendu, Sen, Rupashree, Kundu, Priyanka, Manna, Alak, Sarkar, Avijit, Chowdhury, Chinmay, Chatterjee, Mitali, Das, Padma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593644/ https://www.ncbi.nlm.nih.gov/pubmed/26436418 http://dx.doi.org/10.1371/journal.pone.0139657 |
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