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Inhibitory effects of total saponin from Korean Red Ginseng on [Ca(2+)](i) mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 1,4,5-trisphosphate receptor type I in human platelets

BACKGROUND: Intracellular Ca(2+)([Ca(2+)](i)) is a platelet aggregation-inducing molecule. Therefore, understanding the inhibitory mechanism of [Ca(2+)](i) mobilization is very important to evaluate the antiplatelet effect of a substance. This study was carried out to understand the Ca(2+)-antagonis...

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Detalles Bibliográficos
Autores principales: Shin, Jung-Hae, Kwon, Hyuk-Woo, Cho, Hyun-Jeong, Rhee, Man Hee, Park, Hwa-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593793/
https://www.ncbi.nlm.nih.gov/pubmed/26869828
http://dx.doi.org/10.1016/j.jgr.2015.03.006