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Inhibitory effects of total saponin from Korean Red Ginseng on [Ca(2+)](i) mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 1,4,5-trisphosphate receptor type I in human platelets
BACKGROUND: Intracellular Ca(2+)([Ca(2+)](i)) is a platelet aggregation-inducing molecule. Therefore, understanding the inhibitory mechanism of [Ca(2+)](i) mobilization is very important to evaluate the antiplatelet effect of a substance. This study was carried out to understand the Ca(2+)-antagonis...
Autores principales: | Shin, Jung-Hae, Kwon, Hyuk-Woo, Cho, Hyun-Jeong, Rhee, Man Hee, Park, Hwa-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593793/ https://www.ncbi.nlm.nih.gov/pubmed/26869828 http://dx.doi.org/10.1016/j.jgr.2015.03.006 |
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