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Accurate and Efficient Resolution of Overlapping Isotopic Envelopes in Protein Tandem Mass Spectra

It has long been an analytical challenge to accurately and efficiently resolve extremely dense overlapping isotopic envelopes (OIEs) in protein tandem mass spectra to confidently identify proteins. Here, we report a computationally efficient method, called OIE_CARE, to resolve OIEs by calculating th...

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Detalles Bibliográficos
Autores principales: Xiao, Kaijie, Yu, Fan, Fang, Houqin, Xue, Bingbing, Liu, Yan, Tian, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593959/
https://www.ncbi.nlm.nih.gov/pubmed/26439836
http://dx.doi.org/10.1038/srep14755