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Accurate and Efficient Resolution of Overlapping Isotopic Envelopes in Protein Tandem Mass Spectra
It has long been an analytical challenge to accurately and efficiently resolve extremely dense overlapping isotopic envelopes (OIEs) in protein tandem mass spectra to confidently identify proteins. Here, we report a computationally efficient method, called OIE_CARE, to resolve OIEs by calculating th...
Autores principales: | Xiao, Kaijie, Yu, Fan, Fang, Houqin, Xue, Bingbing, Liu, Yan, Tian, Zhixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593959/ https://www.ncbi.nlm.nih.gov/pubmed/26439836 http://dx.doi.org/10.1038/srep14755 |
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