Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson’s disease

Microglia-mediated neuroinflammation may play an important role in the initiation and progression of dopaminergic (DA) neurodegeneration in Parkinson’s disease (PD), and toll-like receptor 4 (TLR4) is essential for the activation of microglia in the adult brain. However, it is still unclear whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Won-Ho, Jeon, Min-Tae, Leem, Eunju, Won, So-Yoon, Jeong, Kyoung Hoon, Park, Sang-Joon, McLean, Catriona, Lee, Sung Joong, Jin, Byung Kwan, Jung, Un Ju, Kim, Sang Ryoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594003/
https://www.ncbi.nlm.nih.gov/pubmed/26440368
http://dx.doi.org/10.1038/srep14764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594003/
https://www.ncbi.nlm.nih.gov/pubmed/26440368
http://dx.doi.org/10.1038/srep14764

Ejemplares similares