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Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson’s disease
Microglia-mediated neuroinflammation may play an important role in the initiation and progression of dopaminergic (DA) neurodegeneration in Parkinson’s disease (PD), and toll-like receptor 4 (TLR4) is essential for the activation of microglia in the adult brain. However, it is still unclear whether...
Autores principales: | Shin, Won-Ho, Jeon, Min-Tae, Leem, Eunju, Won, So-Yoon, Jeong, Kyoung Hoon, Park, Sang-Joon, McLean, Catriona, Lee, Sung Joong, Jin, Byung Kwan, Jung, Un Ju, Kim, Sang Ryoung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594003/ https://www.ncbi.nlm.nih.gov/pubmed/26440368 http://dx.doi.org/10.1038/srep14764 |
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