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Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines

Organic anion transporter 2 (OAT2) is likely important for renal and hepatic drug elimination. Three variants of the OAT2 peptide sequence have been described – OAT2 transcript variant 1 (OAT2-tv1), OAT2 transcript variant 2 (OAT2-tv2), and OAT2 transcript variant 3 (OAT2-tv3). Early studies helping...

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Detalles Bibliográficos
Autores principales: Hotchkiss, Adam G., Berrigan, Liam, Pelis, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594013/
https://www.ncbi.nlm.nih.gov/pubmed/26500550
http://dx.doi.org/10.3389/fphar.2015.00216