Comparative analysis of pentavalent rotavirus vaccine strains and G8 rotaviruses identified during vaccine trial in Africa

RotaTeqTM is a pentavalent rotavirus vaccine based on a bovine rotavirus genetic backbone in vitro reassorted with human outer capsid genes. During clinical trials of RotaTeqTM in Sub-Saharan Africa, the vaccine efficacy over a 2-year follow-up was lower against the genotypes contained in the vaccin...

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Detalles Bibliográficos
Autores principales: Heylen, Elisabeth, Zeller, Mark, Ciarlet, Max, Lawrence, Jody, Steele, Duncan, Van Ranst, Marc, Matthijnssens, Jelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594120/
https://www.ncbi.nlm.nih.gov/pubmed/26440913
http://dx.doi.org/10.1038/srep14658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594120/
https://www.ncbi.nlm.nih.gov/pubmed/26440913
http://dx.doi.org/10.1038/srep14658

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