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Comparative analysis of pentavalent rotavirus vaccine strains and G8 rotaviruses identified during vaccine trial in Africa
RotaTeqTM is a pentavalent rotavirus vaccine based on a bovine rotavirus genetic backbone in vitro reassorted with human outer capsid genes. During clinical trials of RotaTeqTM in Sub-Saharan Africa, the vaccine efficacy over a 2-year follow-up was lower against the genotypes contained in the vaccin...
Autores principales: | Heylen, Elisabeth, Zeller, Mark, Ciarlet, Max, Lawrence, Jody, Steele, Duncan, Van Ranst, Marc, Matthijnssens, Jelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594120/ https://www.ncbi.nlm.nih.gov/pubmed/26440913 http://dx.doi.org/10.1038/srep14658 |
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