Acid‐sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons

KEY POINTS: The hippocampal CA1 region is highly vulnerable to ischaemic stroke. Two forms of AMPA receptor (AMPAR) plasticity – an anoxic form of long‐term potentiation and a delayed increase in Ca(2+)‐permeable (CP) AMPARs – contribute to this susceptibility by increasing excitotoxicity. In CA1, t...

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Detalles Bibliográficos
Autores principales: Quintana, Patrice, Soto, David, Poirot, Olivier, Zonouzi, Marzieh, Kellenberger, Stephan, Muller, Dominique, Chrast, Roman, Cull‐Candy, Stuart G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Neuroscience ‐ Development/Plasticity/Repair
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594240/
https://www.ncbi.nlm.nih.gov/pubmed/26174503
http://dx.doi.org/10.1113/JP270701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594240/
https://www.ncbi.nlm.nih.gov/pubmed/26174503
http://dx.doi.org/10.1113/JP270701

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