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Acid‐sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons
KEY POINTS: The hippocampal CA1 region is highly vulnerable to ischaemic stroke. Two forms of AMPA receptor (AMPAR) plasticity – an anoxic form of long‐term potentiation and a delayed increase in Ca(2+)‐permeable (CP) AMPARs – contribute to this susceptibility by increasing excitotoxicity. In CA1, t...
Autores principales: | Quintana, Patrice, Soto, David, Poirot, Olivier, Zonouzi, Marzieh, Kellenberger, Stephan, Muller, Dominique, Chrast, Roman, Cull‐Candy, Stuart G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594240/ https://www.ncbi.nlm.nih.gov/pubmed/26174503 http://dx.doi.org/10.1113/JP270701 |
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