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Cell type-specific pharmacology of NMDA receptors using masked MK801

N-Methyl-D-aspartate receptors (NMDA-Rs) are ion channels that are important for synaptic plasticity, which is involved in learning and drug addiction. We show enzymatic targeting of an NMDA-R antagonist, MK801, to a molecularly defined neuronal population with the cell-type-selectivity of genetic m...

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Detalles Bibliográficos
Autores principales: Yang, Yunlei, Lee, Peter, Sternson, Scott M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594264/
https://www.ncbi.nlm.nih.gov/pubmed/26359633
http://dx.doi.org/10.7554/eLife.10206